Scientific News

The impact exposure metal fume and vapor with total IgE and total IgG

Abstract: Blacksmith centers which produce agricultural tools, household appliances, carpentry tools, souvenirs, propeller and other vessels are located in the District Hulu Sungai Selatan, South Kalimantan Province. The Blacksmiths during their works did not use personal protective equipment, they were always exposed to metal fume and vapor, and compounds resulting from the combustion process in a high temperature (>600oC) with results ab normalization in the total IgE and total IgG levels. The objective of the investigation was to assess the impact between exposure of metal fume and vapor with the total IgE and total IgG levels. The study was analytic observational, and cross sectional design conducted in the Districts of Hulu Sungai Selatan, South Kalimantan Province Blood sampling, measuring of metal fume and vapor, were conducted at Kandangan hospital, and Balai Hiperkes and keselamatan Kerja South Kalimantan Province, respectively. Whereas determination of total IgE and total IgG levels was carried out at Prodia laboratory Jakarta - Indonesia. The population of studies was the entire blacksmiths in districts of Hulu Sungai Selatan, South Kalimantan Province, Indonesia. The sampling procedure was based on purposive sampling predefined by inclusion and exclusion criteria with a sample of 38 units and 38 blacksmiths with two population proportion hypothesis. Result were analysed observational, and cross sectional design using logistic regression, and test of Partial Least Square (PLS). Result were logistic regression a significant correlation due to exposure of metal fume, and vapor with the ab normalization total IgE by p:< 0.05; and the Partial Least Square (PLS) indicated the presence of a significant correlation of metal fume, and vapor with the ab normalization of total IgG with R2: 0.1569. In conclusion, this study demonstrates the presence of a positive and significant impact and correlation due to exposure of metal fume and vapors with of total IgE and total IgG levels.

Keywords: Impact; Metal fume and vapor exposure; Total IgE and total IgG serum levels